Title : SAMHD1 Limits the Efficacy of Forodesine in Leukemia by Protecting Cells against the Cytotoxicity of dGTP.

Pub. Date : 2020 May 12

PMID : 32402273






1 Functional Relationships(s)
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1 SAMHD1-deficient cells induce intrinsic apoptosis upon provision of deoxyribonucleosides, particularly deoxyguanosine (dG). Deoxyribonucleosides SAM and HD domain containing deoxynucleoside triphosphate triphosphohydrolase 1 Homo sapiens