Title : The Role of a Selective P2Y6 Receptor Antagonist, MRS2578, on the Formation of Angiotensin II-Induced Abdominal Aortic Aneurysms.

Pub. Date : 2020

PMID : 32382533






1 Functional Relationships(s)
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1 Furthermore, histological analyses showed that administration of MRS2578 significantly increased infiltration of macrophages, expression of monocyte chemotactic protein 1 (MCP-1) and vascular cell adhesion molecule-1 (VCAM-1), and activities of MMP-2 and MMP-9 followed by aggravating degradation elastin in vivo (p < 0.05). N,N''-1,4-butanediylbis(N'-(3-isothiocyanatophenyl))thiourea matrix metallopeptidase 9 Mus musculus