Title : Crystal Structure of Catechol O-Methyltransferase Complexed with Nitecapone.

Pub. Date : 2020

PMID : 32378542






1 Functional Relationships(s)
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1 This interaction seems to play a critical role in the affinity of the inhibitor and to stabilize the COMT/SAM/Mg2+/nitrocatechol inhibitor complex by fixing the flexible alpha2alpha3-loop. nitrocatechol catechol-O-methyltransferase Homo sapiens