Title : New insights into KATP channel gene mutations and neonatal diabetes mellitus.

Pub. Date : 2020 Jul

PMID : 32376986






2 Functional Relationships(s)
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1 Here we review how these structures aid our understanding of how the various mutations in the genes encoding Kir6.2 (KCNJ11) and SUR1 (ABCC8) lead to a reduction in ATP inhibition and thereby neonatal diabetes mellitus. Adenosine Triphosphate ATP binding cassette subfamily C member 8 Homo sapiens
2 Here we review how these structures aid our understanding of how the various mutations in the genes encoding Kir6.2 (KCNJ11) and SUR1 (ABCC8) lead to a reduction in ATP inhibition and thereby neonatal diabetes mellitus. Adenosine Triphosphate ATP binding cassette subfamily C member 8 Homo sapiens