Title : Tsc1 haploinsufficiency in Nkx2.1 cells upregulates hippocampal interneuron mTORC1 activity, impairs pyramidal cell synaptic inhibition, and alters contextual fear discrimination and spatial working memory in mice.

Pub. Date : 2020 May 6

PMID : 32375878






1 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 TSC1 and TSC2 are repressors of the mechanistic target of rapamycin complex 1 (mTORC1), a key regulator of protein synthesis. Sirolimus TSC complex subunit 1 Mus musculus