Title : Drugs as allergens: detection and combining site specificities of IgE antibodies to sulfamethoxazole.

Pub. Date : 1988 Dec

PMID : 3237218






3 Functional Relationships(s)
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1 An immunoassay was developed for the detection of sulfamethoxazole reactive IgE antibodies in the sera of patients who experienced life threatening anaphylactic reactions following the ingestion of co-trimoxazole (trimethoprim and sulfamethoxazole). Trimethoprim, Sulfamethoxazole Drug Combination immunoglobulin heavy constant epsilon Homo sapiens
2 The assays for the detection of IgE antibodies to sulfamethoxazole and trimethoprim should prove useful for the diagnosis of immediate hypersensitivity to co-trimoxazole and perhaps for monitoring drug therapy in AIDS patients where a high incidence of adverse reactions to co-trimoxazole has been reported. Trimethoprim, Sulfamethoxazole Drug Combination immunoglobulin heavy constant epsilon Homo sapiens
3 The assays for the detection of IgE antibodies to sulfamethoxazole and trimethoprim should prove useful for the diagnosis of immediate hypersensitivity to co-trimoxazole and perhaps for monitoring drug therapy in AIDS patients where a high incidence of adverse reactions to co-trimoxazole has been reported. Trimethoprim, Sulfamethoxazole Drug Combination immunoglobulin heavy constant epsilon Homo sapiens