Title : Leucine Supplementation: A Novel Strategy for Modulating Lipid Metabolism and Energy Homeostasis.

Pub. Date : 2020 May 2

PMID : 32370170






1 Functional Relationships(s)
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1 This review offers an up-to-date report on leucine, as key roles in both lipid metabolism and energy homeostasis in vivo and in vitro by acceleration of fatty acid oxidation, lipolysis, activation of the adenosine 5"-monophosphate-activated protein kinase (AMPK)-silent information regulator of transcription 1 (SIRT1)-proliferator-activated receptor gamma coactivator-1alpha (PGC-1alpha) pathway, synthesis, and/or secretion of adipokines and stability of the gut microbiota. Leucine sirtuin 1 Homo sapiens