Title : CDK9 inhibitor CDKI-73 is synergetic lethal with PARP inhibitor olaparib in BRCA1 wide-type ovarian cancer.

Pub. Date : 2020

PMID : 32368391






1 Functional Relationships(s)
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1 Poly (adenosine diphosphate ribose) polymerase (PARP) inhibitors benefit a small percentage of ovarian cancer patients with homologous recombination (HR) deficiency (HRD), which greatly limits the applications of PARP inhibitors. Adenosine poly(ADP-ribose) polymerase 1 Homo sapiens