Title : Letter to the Editor: Blocking Sodum-Taurocholate Cotransporting Polypeptide Stimulates Biliary Cholesterol and Phospholipid Secretion in Mice.

Pub. Date : 2020 Nov

PMID : 32367585






1 Functional Relationships(s)
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1 The recent report (1) that the increased cholesterol and lecithin content of hepatic bile after administration of the complex lipopeptide myrcludex B is attributable to its binding to the Sodium Taurocholate Cotransporting Polypeptide (NTCP) , which causes a re-distribution of canalicular bile transport to the peri-central zone appears to conflict with a previous study (2). Lecithins solute carrier family 10 (sodium/bile acid cotransporter family), member 1 Mus musculus