Pub. Date : 2020
PMID : 32365105
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | In addition, thrombin increased prostaglandin-endoperoxidase synthase-2 (PTGS2 or COX2) mRNA and prostaglandin E2 and F2alpha synthesis in human myometrial cells. | Prostaglandins | coagulation factor II, thrombin | Homo sapiens |
| 2 | Thrombin significantly increased the mRNA level of interleukine-1beta, whereas it decreased the expressions of prostaglandin EP3 and F2alpha receptors. | Prostaglandins | coagulation factor II, thrombin | Homo sapiens |
| 3 | Collectively, thrombin induces myometrial contractions by two mechanisms, including direct activation of myosin and indirect increases in prostaglandin synthesis. | Prostaglandins | coagulation factor II, thrombin | Homo sapiens |