Title : Insights into P-Glycoprotein Inhibitors: New Inducers of Immunogenic Cell Death.

Pub. Date : 2020 Apr 22

PMID : 32331368






2 Functional Relationships(s)
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1 Indeed, Pgp effluxes doxorubicin and impairs the immunesensitizing functions of calreticulin (CRT), an "eat-me" signal mediating ICD. Doxorubicin ATP binding cassette subfamily B member 1 Homo sapiens
2 Pgp knock-out restores doxorubicin-induced ICD in MDA-MB-231/DX cells that recapitulated the phenotype of R-3-treated cells. Doxorubicin ATP binding cassette subfamily B member 1 Homo sapiens