Title : Association of Oral Anticoagulants and Verapamil or Diltiazem With Adverse Bleeding Events in Patients With Nonvalvular Atrial Fibrillation and Normal Kidney Function.

Pub. Date : 2020 Apr 1

PMID : 32329770






3 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 Verapamil hydrochloride and diltiazem hydrochloride are combined P-glycoprotein (P-gp) and CYP3A4 inhibitors and may be associated with increases in the risk of bleeding with DOACs. Verapamil ATP binding cassette subfamily B member 1 Homo sapiens
2 Verapamil hydrochloride and diltiazem hydrochloride are combined P-glycoprotein (P-gp) and CYP3A4 inhibitors and may be associated with increases in the risk of bleeding with DOACs. Verapamil ATP binding cassette subfamily B member 1 Homo sapiens
3 This study found increased bleeding risk associated with dabigatran when used concomitantly with the P-gp inhibitors verapamil and diltiazem in individuals with normal kidney function. Verapamil ATP binding cassette subfamily B member 1 Homo sapiens