Pub. Date : 2020 Sep
PMID : 32313198
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | In vitro investigations showed that PPARbeta/delta deficiency in fibroblasts increased epidermal Nox4-derived H2O2 production, which triggered an NRF2-mediated antioxidant response. | Hydrogen Peroxide | nuclear factor, erythroid derived 2, like 2 | Mus musculus |
| 2 | We further showed that H2O2 upregulated NRF2 mRNA via the B-Raf-MEK1/2 pathway. | Hydrogen Peroxide | nuclear factor, erythroid derived 2, like 2 | Mus musculus |