Title : The anti-fibrotic actions of relaxin are mediated through AT2 R-associated protein phosphatases via RXFP1-AT2 R functional crosstalk in human cardiac myofibroblasts.

Pub. Date : 2020 Jun

PMID : 32297670






1 Functional Relationships(s)
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1 These findings demonstrated that RLX can indirectly activate AT2 R-dependent phosphatase activity in HCMFs by signaling through RXFP1-AT2 R crosstalk, which have important therapeutic implications for its anti-fibrotic actions. Relaxin relaxin family peptide receptor 1 Homo sapiens