Title : RNase L Amplifies Interferon Signaling by Inducing Protein Kinase R-Mediated Antiviral Stress Granules.

Pub. Date : 2020 Jun 16

PMID : 32295917






1 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 Both cellular and viral RNA cleavage products of RNase L bind pattern recognition receptors (PRR) like Retinoic acid-inducible I (Rig-I) and or melanoma differentiation-associated protein 5 (MDA5) to further amplify interferon (IFN) production and antiviral response. Tretinoin DExD/H-box helicase 58 Homo sapiens