Title : Remdesivir and SARS-CoV-2: Structural requirements at both nsp12 RdRp and nsp14 Exonuclease active-sites.

Pub. Date : 2020 Jun

PMID : 32283108






1 Functional Relationships(s)
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1 To date, the most promising broad-spectrum class of viral RdRp inhibitors are nucleoside analogues (NAs), with over 25 approved for the treatment of several medically important viral diseases. Nucleosides ORF1a polyprotein;ORF1ab polyprotein Severe acute respiratory syndrome coronavirus 2