Title : Shikonin mitigates ovariectomy-induced bone loss and RANKL-induced osteoclastogenesis via TRAF6-mediated signaling pathways.

Pub. Date : 2020 Jun

PMID : 32272431






2 Functional Relationships(s)
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1 At the molecular level, Western blot analysis indicated that shikonin inhibited the phosphorylation of inhibitor of NF-kappaB (IkappaB), P50, P65, extracellular regulated protein kinases (ERK), c-Jun N-terminal kinase (JNK), and P38. shikonin nuclear factor of kappa light polypeptide gene enhancer in B cells 1, p105 Mus musculus
2 At the molecular level, Western blot analysis indicated that shikonin inhibited the phosphorylation of inhibitor of NF-kappaB (IkappaB), P50, P65, extracellular regulated protein kinases (ERK), c-Jun N-terminal kinase (JNK), and P38. shikonin nuclear factor of kappa light polypeptide gene enhancer in B cells 1, p105 Mus musculus