Title : Neuronal CXCL10/CXCR3 Axis Mediates the Induction of Cerebral Hyperexcitability by Peripheral Viral Challenge.

Pub. Date : 2020

PMID : 32265633






3 Functional Relationships(s)
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1 injection of a viral mimetic, polyinosinic-polycytidylic acid (PIC) induces a robust generation of CXCL10 chemokine in the hippocampus. Poly I-C chemokine (C-X-C motif) ligand 10 Mus musculus
2 injection of a viral mimetic, polyinosinic-polycytidylic acid (PIC) induces a robust generation of CXCL10 chemokine in the hippocampus. Poly I-C chemokine (C-X-C motif) ligand 10 Mus musculus
3 The present study was undertaken to determine the role of CXCL10 in mediating the development of hyperexcitability in response to PIC challenge. Poly I-C chemokine (C-X-C motif) ligand 10 Mus musculus