Pub. Date : 2020 Apr
PMID : 32256770
4 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | Effects of mevalonate kinase interference on cell differentiation, apoptosis, prenylation and geranylgeranylation of human keratinocytes are attenuated by farnesyl pyrophosphate or geranylgeranyl pyrophosphate. | geranylgeranyl pyrophosphate | mevalonate kinase | Homo sapiens |
2 | Furthermore, the apoptotic rate was markedly increased following MVK interference, and the increase was significantly attenuated by GGPP. | geranylgeranyl pyrophosphate | mevalonate kinase | Homo sapiens |
3 | The prenylation levels after MVK interference was notably decreased, which was markedly attenuated by GGPP. | geranylgeranyl pyrophosphate | mevalonate kinase | Homo sapiens |
4 | FPP or GGPP reversed MVK interference-induced decrease in geranylgeranylation levels of lamin A, HRAS, KRAS, NRAS, Rho E, Rho B, Rho A, RAC1 and cdc42. | geranylgeranyl pyrophosphate | mevalonate kinase | Homo sapiens |