Title : Design of dual drug-loaded dendrimer/carbon dot nanohybrids for fluorescence imaging and enhanced chemotherapy of cancer cells.

Pub. Date : 2019 Jan 14

PMID : 32254552






1 Functional Relationships(s)
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1 We showed that the nanohybrids possessed good colloidal stability and enabled significant inhibition of cancer cells due to the presence of TPGS, which can inhibit P-glycoprotein (P-gp) by decreasing ATP levels and increasing ROS levels; simultaneously, fluorescence imaging of cancer cells could be achieved in vitro due to the luminescence of CDs. Adenosine Triphosphate ATP binding cassette subfamily B member 1 Homo sapiens