Title : Loss of lenalidomide-induced megakaryocytic differentiation leads to therapy resistance in del(5q) myelodysplastic syndrome.

Pub. Date : 2020 May

PMID : 32251398






1 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 Megakaryocytic gene-promoter analyses suggested that LEN-induced degradation of IKZF1 enables a RUNX1-GATA2 complex to drive megakaryocytic differentiation. Lenalidomide RUNX family transcription factor 1 Homo sapiens