Title : Effects of repeated oral doses of ketoconazole on a sequential ascending single oral dose of fedratinib in healthy subjects.

Pub. Date : 2020 May

PMID : 32248324






1 Functional Relationships(s)
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1 The primary objective of this study was to evaluate the effects of 14-day repeated 200 mg twice daily (BID) oral doses of a strong CYP3A4 inhibitor, ketoconazole, on a sequential ascending single oral dose of fedratinib in healthy male subjects. Ketoconazole cytochrome P450 family 3 subfamily A member 4 Homo sapiens