Title : Enhancing the sensitivity of the thymidine kinase assay by using DNA repair-deficient human TK6 cells.

Pub. Date : 2020 Jul

PMID : 32243652






1 Functional Relationships(s)
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1 The usage of XRCC1-/- /XPA-/- cells increased the sensitivity of detecting the mutagenicity by 8.6 times for MMC, 8.5 times for CDDP, and 2.6 times for MMS in comparison with the conventional TK assay. Methyl Methanesulfonate X-ray repair cross complementing 1 Homo sapiens