Title : Neuroprotective effects of mirtazapine and imipramine and their effect in pro- and anti-apoptotic gene expression in human neuroblastoma cells.

Pub. Date : 2020 Jun

PMID : 32240535






2 Functional Relationships(s)
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1 METHODS: SH-SY5Y cells were preincubated with mirtazapine and imipramine (1-20 muM) for 24 h, then hydrogen peroxide (H2O2) was added into the medium containing the antidepressants for additional 24 h, and MTT assay was carried out subsequently. Imipramine latexin Homo sapiens
2 Also, to elucidate the molecular mechanism underlying the neuroprotective properties of antidepressants, we investigated the effects of mirtazapine and imipramine (2 muM) in pro- and anti-apoptotic proteins gene expression in SH-SY5Y cells. Imipramine latexin Homo sapiens