Title : Solvent dynamics play a decisive role in the complex formation of biologically relevant redox proteins.

Pub. Date : 2020 Apr 8

PMID : 32215444






2 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 Binding of the FNR:PetF complex to the substrate NADP+ results in bulk-like solvent dynamics of 7 ps, showing that formation of the ternary complex is entropically favored. NADP ferredoxin reductase Homo sapiens
2 Complex formation between the positively charged FNR:NADP+ pre-complex and the negatively charged PetF is not only entropically favored, but in addition the solvent reorganization into more bulk-like water assists the molecular recognition process. NADP ferredoxin reductase Homo sapiens