Pub. Date : 2020 Apr
PMID : 32199253
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | beta-Elemene inhibits the metastasis of multidrug-resistant gastric cancer cells through miR-1323/Cbl-b/EGFR pathway. | beta-elemene | epidermal growth factor receptor | Homo sapiens |
| 2 | Further studies showed that beta-Elemene upregulated Cbl-b expression, resulting in inhibition of the EGFR-ERK/AKT pathways, which regulate MMP-2/9. | beta-elemene | epidermal growth factor receptor | Homo sapiens |
| 3 | CONCLUSION: Our results suggested that beta-Elemene inhibits the metastasis of MDR gastric cancer cells by modulating the miR-1323/Cbl-b/EGFR signaling axis. | beta-elemene | epidermal growth factor receptor | Homo sapiens |