Title : Upregulated LEPRE1 correlates with poor outcome and its knockdown attenuates cells proliferation, migration and invasion in osteosarcoma.

Pub. Date : 2020 Apr

PMID : 32197005






3 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 Additionally, we detected the role of leucine proline-enriched proteoglycan 1 knockdown on PI3K/AKT pathway-related proteins using western blotting. Proline AKT serine/threonine kinase 1 Homo sapiens
2 Furthermore, the expression of phosphorylated PI3K and AKT was impaired after knockdown the leucine proline-enriched proteoglycan 1 as well as P70S6K. Proline AKT serine/threonine kinase 1 Homo sapiens
3 In conclusion, leucine proline-enriched proteoglycan 1 might function as an important therapeutic factor in human osteosarcoma through regulating the PI3K/AKT signaling pathway. Proline AKT serine/threonine kinase 1 Homo sapiens