Title : Zhx2 Accelerates Sepsis by Promoting Macrophage Glycolysis via Pfkfb3.

Pub. Date : 2020 Apr 15

PMID : 32179636






1 Functional Relationships(s)
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1 Furthermore, Pfkfb3 overexpression not only rescued the reduction of macrophage glycolysis caused by Zhx2 deficiency, displaying as extracellular acidification rates and lactate production but also destroyed the resistance of mice to LPS-induced sepsis initiated by transfer of bone marrow-derived macrophages from MKO mice. Lactic Acid 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3 Mus musculus