Title : Inverse screening of Simvastatin kinase targets from glioblastoma druggable kinome.

Pub. Date : 2020 Jun

PMID : 32172201






1 Functional Relationships(s)
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1 It is revealed that Simvastatin can potentially interact with certain known targets or key regulators of GBM such as ErbB, c-Src and FGFR signaling pathways, but exhibit low affinity to the well-established GBM target of PI3K/Akt/mTOR pathway. Simvastatin AKT serine/threonine kinase 1 Homo sapiens