Pub. Date : 2020 May 6
PMID : 32166890
5 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Lysine-specific demethylase 1 (LSD1) is a flavin adenine dinucleotide (FAD)-dependent enzyme that catalyzes the demethylation of histone H3 and regulates gene expression. | Flavin-Adenine Dinucleotide | lysine demethylase 1A | Homo sapiens |
| 2 | Lysine-specific demethylase 1 (LSD1) is a flavin adenine dinucleotide (FAD)-dependent enzyme that catalyzes the demethylation of histone H3 and regulates gene expression. | Flavin-Adenine Dinucleotide | lysine demethylase 1A | Homo sapiens |
| 3 | Lysine-specific demethylase 1 (LSD1) is a flavin adenine dinucleotide (FAD)-dependent enzyme that catalyzes the demethylation of histone H3 and regulates gene expression. | Flavin-Adenine Dinucleotide | lysine demethylase 1A | Homo sapiens |
| 4 | Lysine-specific demethylase 1 (LSD1) is a flavin adenine dinucleotide (FAD)-dependent enzyme that catalyzes the demethylation of histone H3 and regulates gene expression. | Flavin-Adenine Dinucleotide | lysine demethylase 1A | Homo sapiens |
| 5 | Structural analyses of LSD1 co-crystallized with S2101, S2116, S2157, or another N -alkylated inhibitor (FCPA-MPE) confirmed that the N -substituents enhance the potency of a 2-PCPA-based inhibitor of LSD1, without constituting the adduct formed with FAD. | Flavin-Adenine Dinucleotide | lysine demethylase 1A | Homo sapiens |