Title : Intranasal Delivery of Bone Marrow Stromal Cells Preconditioned with Fasudil to Treat a Mouse Model of Parkinson's Disease.

Pub. Date : 2020

PMID : 32158210






3 Functional Relationships(s)
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1 Results: Our study showed that fasudil could accelerate the proliferation of BMSCs and promote brain-derived neurotrophic factor (BDNF) secretion in vitro. fasudil brain derived neurotrophic factor Mus musculus
2 Results: Our study showed that fasudil could accelerate the proliferation of BMSCs and promote brain-derived neurotrophic factor (BDNF) secretion in vitro. fasudil brain derived neurotrophic factor Mus musculus
3 Preconditioning with fasudil inhibited the activation and aggregation of microglia, suppressed immune response, and reinforced BDNF secretion in MPTP-PD mice significantly more than treatment with BMSCs alone. fasudil brain derived neurotrophic factor Mus musculus