Title : Metformin and heart failure-related outcomes in patients with or without diabetes: a systematic review of randomized controlled trials.

Pub. Date : 2021 Nov

PMID : 32157481






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1 Effective modulation of some heart failure-related outcomes with metformin treatment was related to its beneficial effects in ameliorating insulin resistance and blocking pro-inflammatory markers such as the aging-associated cytokine CCL11 (C-C motif chemokine ligand 11). Metformin insulin Homo sapiens