Title : Two-Dimensional Cellular and Three-Dimensional Bio-Printed Skin Models to Screen Topical-Use Compounds for Irritation Potential.

Pub. Date : 2020

PMID : 32154236






2 Functional Relationships(s)
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1 Among known irritants, high concentrations of methyl violet and methylrosaniline decreased viability, lowered TEER, and increased IL-1alpha secretion in both RhE and FTS models, consistent with irritant properties. Gentian Violet factor interacting with PAPOLA and CPSF1 Homo sapiens
2 Among known irritants, high concentrations of methyl violet and methylrosaniline decreased viability, lowered TEER, and increased IL-1alpha secretion in both RhE and FTS models, consistent with irritant properties. Gentian Violet factor interacting with PAPOLA and CPSF1 Homo sapiens