Pub. Date : 2020 Mar
PMID : 32147975
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | The macrolide antibiotic erythromycin has been associated with QT interval prolongation and inhibition of the hERG-encoded channels responsible for the rapid delayed rectifier K+ current I(Kr ). | Erythromycin | ETS transcription factor ERG | Homo sapiens |
| 2 | It has been suggested that low concentrations of erythromycin may have a protective effect against hERG block and associated drug-induced arrhythmia by reducing the affinity of the pore-binding site for high potency hERG inhibitors. | Erythromycin | ETS transcription factor ERG | Homo sapiens |