Pub. Date : 2020 Mar 2
PMID : 32119644
4 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Silencing MR or deleting mannose residues on Env rescues Env expression in HIV-1-infected macrophages lacking Vpr. | Mannose | Envelope surface glycoprotein gp160, precursor | Human immunodeficiency virus 1 |
| 2 | Silencing MR or deleting mannose residues on Env rescues Env expression in HIV-1-infected macrophages lacking Vpr. | Mannose | Envelope surface glycoprotein gp160, precursor | Human immunodeficiency virus 1 |
| 3 | Together these results reveal a Vpr-Nef-Env axis that hijacks a host mannose-MR response system to facilitate infection while evading MR"s normal role, which is to trap and destroy mannose-expressing pathogens. | Mannose | Envelope surface glycoprotein gp160, precursor | Human immunodeficiency virus 1 |
| 4 | Together these results reveal a Vpr-Nef-Env axis that hijacks a host mannose-MR response system to facilitate infection while evading MR"s normal role, which is to trap and destroy mannose-expressing pathogens. | Mannose | Envelope surface glycoprotein gp160, precursor | Human immunodeficiency virus 1 |