Title : Acetylcholinesterase inhibitory activity and neuroprotection in vitro, molecular docking, and improved learning and memory functions of demethylcurcumin in scopolamine-induced amnesia ICR mice.

Pub. Date : 2020 Mar 1

PMID : 32118214






2 Functional Relationships(s)
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1 Based on molecular docking analyses with AChE, the meta-hydroxyl group in DC, nonexistent in curcumin, showed the formation of hydrogen bonds with Ser293 and Tyr341 in the binding sites of AChE. Hydrogen acetylcholinesterase (Cartwright blood group) Homo sapiens
2 Based on molecular docking analyses with AChE, the meta-hydroxyl group in DC, nonexistent in curcumin, showed the formation of hydrogen bonds with Ser293 and Tyr341 in the binding sites of AChE. Hydrogen acetylcholinesterase (Cartwright blood group) Homo sapiens