Title : Activation of PGC-1α and Mitochondrial Biogenesis Protects Against Prenatal Hypoxic-ischemic Brain Injury.

Pub. Date : 2020 Apr 15

PMID : 32114097






2 Functional Relationships(s)
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1 Postnatal administration of pioglitazone further promoted PGC-1alpha and mitochondrial biogenesis, alleviated hippocampal injury, and improved performance in the behavioral tasks after intrauterine HI. Pioglitazone PPARG coactivator 1 alpha Homo sapiens
2 Promotion of PGC-1alpha by pioglitazone might be a potential treatment for protecting against hippocampal injury and cognitive defects after intrauterine HI. Pioglitazone PPARG coactivator 1 alpha Homo sapiens