Pub. Date : 2020 Apr 10
PMID : 32111736
8 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | In vivo FRET analyses reveal a role of ATP hydrolysis-associated conformational changes in human P-glycoprotein. | Adenosine Triphosphate | ATP binding cassette subfamily B member 1 | Homo sapiens |
| 2 | P-glycoprotein (P-gp; also known as MDR1 or ABCB1) is an ATP-driven multidrug transporter that extrudes various hydrophobic toxic compounds to the extracellular space. | Adenosine Triphosphate | ATP binding cassette subfamily B member 1 | Homo sapiens |
| 3 | P-glycoprotein (P-gp; also known as MDR1 or ABCB1) is an ATP-driven multidrug transporter that extrudes various hydrophobic toxic compounds to the extracellular space. | Adenosine Triphosphate | ATP binding cassette subfamily B member 1 | Homo sapiens |
| 4 | P-glycoprotein (P-gp; also known as MDR1 or ABCB1) is an ATP-driven multidrug transporter that extrudes various hydrophobic toxic compounds to the extracellular space. | Adenosine Triphosphate | ATP binding cassette subfamily B member 1 | Homo sapiens |
| 5 | P-glycoprotein (P-gp; also known as MDR1 or ABCB1) is an ATP-driven multidrug transporter that extrudes various hydrophobic toxic compounds to the extracellular space. | Adenosine Triphosphate | ATP binding cassette subfamily B member 1 | Homo sapiens |
| 6 | P-gp consists of two transmembrane domains (TMDs) that form the substrate translocation pathway and two nucleotide-binding domains (NBDs) that bind and hydrolyze ATP. | Adenosine Triphosphate | ATP binding cassette subfamily B member 1 | Homo sapiens |
| 7 | In this study, we used a new FRET sensor that detects conformational changes in P-gp to investigate the role of ATP binding and hydrolysis during the conformational changes of human P-gp in living HEK293 cells. | Adenosine Triphosphate | ATP binding cassette subfamily B member 1 | Homo sapiens |
| 8 | In this study, we used a new FRET sensor that detects conformational changes in P-gp to investigate the role of ATP binding and hydrolysis during the conformational changes of human P-gp in living HEK293 cells. | Adenosine Triphosphate | ATP binding cassette subfamily B member 1 | Homo sapiens |