Title : Spiraea prunifolia var. simpliciflora Attenuates Oxidative Stress and Inflammatory Responses in a Murine Model of Lipopolysaccharide-Induced Acute Lung Injury and TNF-α-Stimulated NCI-H292 Cells.

Pub. Date : 2020 Feb 26

PMID : 32111036






2 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 SP decreased the number of inflammatory cells and the levels of TNF-alpha, interleukin (IL)-1beta, and IL-6 in the bronchoalveolar lavage fluid, and inflammatory cell infiltration in the lung tissues of SP-treated mice. sp tumor necrosis factor Mus musculus
2 SP significantly suppressed the phosphorylation of the mitogen-activated protein kinases (MAPKs) and p65-nuclear factor-kappa B (NF-kappaB) in LPS-induced ALI mice and TNF-alpha-stimulated NCI-H292 cells. sp tumor necrosis factor Mus musculus