Title : Inverse Agonistic Activity of Antihistamines and Suppression of Histamine H1 Receptor Gene Expression.

Pub. Date : 2012

PMID : 32092833






1 Functional Relationships(s)
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1 These results suggest that inverse agonists more potently alleviate allergy symptoms by not only inhibiting stimulus-induced up-regulation of H1R gene expression but also by suppressing basal histamine signaling through their inverse agonistic activity. Histamine histamine receptor H1 Homo sapiens