Title : Hexosamine Pathway Activation Improves Protein Homeostasis through the Integrated Stress Response.

Pub. Date : 2020 Mar 27

PMID : 32086012






1 Functional Relationships(s)
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1 Activation of the hexosamine pathway (HP) through gain-of-function mutations in its rate-limiting enzyme glutamine fructose-6-phosphate amidotransferase (GFAT-1) ameliorates proteotoxicity and increases lifespan in Caenorhabditis elegans. Hexosamines Glutamine--fructose-6-phosphate transaminase (isomerizing) Caenorhabditis elegans