Title : Hexosamine Pathway Activation Improves Protein Homeostasis through the Integrated Stress Response.

Pub. Date : 2020 Mar 27

PMID : 32086012






2 Functional Relationships(s)
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Sentence
Compound Name
Protein Name
Organism
1 Increasing uridine 5"-diphospho-N-acetyl-D-glucosamine (UDP-GlcNAc) levels through GFAT1 gain-of-function mutations or supplementation with the precursor GlcNAc reduces aggregation of the polyglutamine (polyQ) protein Ataxin-3. polyglutamine Glutamine--fructose-6-phosphate transaminase (isomerizing) Caenorhabditis elegans
2 Increasing uridine 5"-diphospho-N-acetyl-D-glucosamine (UDP-GlcNAc) levels through GFAT1 gain-of-function mutations or supplementation with the precursor GlcNAc reduces aggregation of the polyglutamine (polyQ) protein Ataxin-3. polyglutamine Glutamine--fructose-6-phosphate transaminase (isomerizing) Caenorhabditis elegans