Title : Natural protoberberine alkaloids, identified as potent selective LSD1 inhibitors, induce AML cell differentiation.

Pub. Date : 2020 Apr

PMID : 32065882






2 Functional Relationships(s)
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1 Among these protoberberine alkaloids, epiberberine potently inhibited LSD1 (IC50 = 0.14 +- 0.01 muM) and was highly selective to LSD1 over MAO-A/B. epiberberine lysine demethylase 1A Homo sapiens
2 Among these protoberberine alkaloids, epiberberine potently inhibited LSD1 (IC50 = 0.14 +- 0.01 muM) and was highly selective to LSD1 over MAO-A/B. epiberberine lysine demethylase 1A Homo sapiens