Pub. Date : 2020
PMID : 32064171
4 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | We have previously reported that a conserved cysteine in the MXXCW motif of RET is crucial to the disulfide-bonded dimerization-linked activation of RET kinases. | Cysteine | ret proto-oncogene | Homo sapiens |
| 2 | We have previously reported that a conserved cysteine in the MXXCW motif of RET is crucial to the disulfide-bonded dimerization-linked activation of RET kinases. | Cysteine | ret proto-oncogene | Homo sapiens |
| 3 | Reagents which bind to this cysteine may inhibit the activity of RET kinases through disulfide-bond mediated dimerization. | Cysteine | ret proto-oncogene | Homo sapiens |
| 4 | The great potency of these cysteine targeted peptides could indicate promising approaches for novel molecular-targeted therapies for RET-associated cancers. | Cysteine | ret proto-oncogene | Homo sapiens |