Title : Biliary damage and liver fibrosis are ameliorated in a novel mouse model lacking l-histidine decarboxylase/histamine signaling.

Pub. Date : 2020 Jun

PMID : 32054995






1 Functional Relationships(s)
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1 Multidrug resistance-2 gene knockout (Mdr2-/-) mice and PSC patients have increased histamine (HA) levels (synthesized by l-histidine decarboxylase, HDC) and HA receptor (HR) expression. Histamine histidine decarboxylase Homo sapiens