Title : In vitro comparison of the cytotoxic effects of statins on U266 myeloma cell line.

Pub. Date : 2019 Dec

PMID : 32048627






2 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 Inhibitor concentration 50 (IC50) values calculated for atorvastatin and simvastatin were determined as 94 and 38 muM, respectively. Simvastatin latexin Homo sapiens
2 When six concentrations of bortezomib used in the study were combined with 12.5 muM inactive concentrations of statins that did not cause inhibition in cell proliferation, both atorvastatin and simvastatin increased the effect of bortezomib at all the concentrations used, and simvastatin showed a stronger efficacy than atorvastatin. Simvastatin latexin Homo sapiens