Title : Choroid plexus LAT2 and SNAT3 as partners in CSF amino acid homeostasis maintenance.

Pub. Date : 2020 Feb 11

PMID : 32046769






2 Functional Relationships(s)
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1 In a LAT2 knock-out mouse model, CSF Gln was unchanged, whereas other amino acids normally 2-20-fold lower than in plasma, were increased, in particular the LAT2 uptake substrates leucine (Leu), valine (Val) and tryptophan (Trp) and some other amino acids such as glutamate (Glu), glycine (Gly) and proline (Pro). Tryptophan linker for activation of T cells family, member 2 Mus musculus
2 In a LAT2 knock-out mouse model, CSF Gln was unchanged, whereas other amino acids normally 2-20-fold lower than in plasma, were increased, in particular the LAT2 uptake substrates leucine (Leu), valine (Val) and tryptophan (Trp) and some other amino acids such as glutamate (Glu), glycine (Gly) and proline (Pro). Tryptophan linker for activation of T cells family, member 2 Mus musculus