Title : Predictive biomarkers for immune checkpoint blockade and opportunities for combination therapies.

Pub. Date : 2019 Sep

PMID : 32042863






1 Functional Relationships(s)
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1 Biomarkers will allow clinicians to practice a precision medicine approach in ICBs (biomarker-based patient selection) such as treating triple-negative breast cancer patients that exhibit PD-L1 staining of tumor-infiltrating immune cells in >=1% of the tumor area with nanoparticle albumin-bound (nab)-paclitaxel plus anti-PD-L1 and treating patients of MSI-H or MMR deficient unresectable or metastatic solid tumors with pembrolizumab (anti-PD-1). nab CD274 molecule Homo sapiens