Title : PolyG mitigates silica-induced pulmonary fibrosis by inhibiting nucleolin and regulating DNA damage repair pathway.

Pub. Date : 2020 May

PMID : 32036217






1 Functional Relationships(s)
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1 PolyG could efficiently reduce the protein expression of gamma-H2AX and decreased the level of fibrosis-related genes, such as Col1a1 and Col3a1, as well as the levels of fibrosis-associated proteins alpha-SMA and vimentin in the lungs of silica-treated mice. Poly G actin alpha 2, smooth muscle, aorta Mus musculus