Pub. Date : 2020 Feb 28
PMID : 32031205
4 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | Sec-O-glucosylhamaudol suppressed inflammatory reaction induced by LPS in RAW264.7 cells through inhibition of NF-kappaB and MAPKs signaling. | 11-hydroxy-sec-O-glucosylhamaudol | toll-like receptor 4 | Mus musculus |
2 | The anti-inflammatory impacts of SOG in RAW 264.7 cell lines stimulated by LPS were explored in the present study. | 11-hydroxy-sec-O-glucosylhamaudol | toll-like receptor 4 | Mus musculus |
3 | It was found that SOG dose-dependently reduced the emergence of inflammation cytokines, such as IL-6 and TNF-alpha in Raw264.7 murine macrophages stimulated by LPS. | 11-hydroxy-sec-O-glucosylhamaudol | toll-like receptor 4 | Mus musculus |
4 | In addition, it was also found that NF-kappaB activation and MAPKs phosphorylation including p38, JNK and ERK1/2 induced by LPS were suppressed by SOG. | 11-hydroxy-sec-O-glucosylhamaudol | toll-like receptor 4 | Mus musculus |