Title : Sec-O-glucosylhamaudol suppressed inflammatory reaction induced by LPS in RAW264.7 cells through inhibition of NF-κB and MAPKs signaling.

Pub. Date : 2020 Feb 28

PMID : 32031205






4 Functional Relationships(s)
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1 Sec-O-glucosylhamaudol suppressed inflammatory reaction induced by LPS in RAW264.7 cells through inhibition of NF-kappaB and MAPKs signaling. 11-hydroxy-sec-O-glucosylhamaudol toll-like receptor 4 Mus musculus
2 The anti-inflammatory impacts of SOG in RAW 264.7 cell lines stimulated by LPS were explored in the present study. 11-hydroxy-sec-O-glucosylhamaudol toll-like receptor 4 Mus musculus
3 It was found that SOG dose-dependently reduced the emergence of inflammation cytokines, such as IL-6 and TNF-alpha in Raw264.7 murine macrophages stimulated by LPS. 11-hydroxy-sec-O-glucosylhamaudol toll-like receptor 4 Mus musculus
4 In addition, it was also found that NF-kappaB activation and MAPKs phosphorylation including p38, JNK and ERK1/2 induced by LPS were suppressed by SOG. 11-hydroxy-sec-O-glucosylhamaudol toll-like receptor 4 Mus musculus